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soul trial oral semaglutide cardiovascular outcomes trial An oral formulation of semaglutide lowered the risk major adverse cardiovascular events by 14% in four years, with no change in safety profile compared to placebo, according to the SOUL study. #ACC25

Marsoni M251S
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4.8 ★★★★★
Based on 110 reviews
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Verified Purchase
Pooh
Charlottesville, US
★★★★★ 5
Very Small
These are tiny! Just perfect for my little dogs but one was lost within the first few minutes so I had to order another. I'm not so sure how safe it is for the fur children to chew on non-edible, non-digestible plastics but they seem to really like them.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 28, 2025
K
Verified Purchase
Kristi S
Carnegie, US
★★★★★ 5
A Hit with Both My Puppy and Older Dog!
I bought the Nylabone Moderate Chew FlexiChew Bone in the peanut butter and bacon flavor for my new puppy, and he absolutely loves them! What’s even better is that my other dog is just as obsessed with them, so it's been a hit with both. The size is perfect for my tiny puppy, and the flavor keeps them both engaged for a long time. These bones are durable enough to last, even with moderate chewing, and they help satisfy their natural chewing instincts. If you’re looking for a great chew toy for both puppies and small dogs, I highly recommend these Nylabones. They’re a definite favorite in our household!
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Reviewed in the United States on October 11, 2024
E
Verified Purchase
Emily Cary
Los Angeles, US
★★★★★ 5
Dog loves them.
Size: Medium, Style: Beef
They make excellent toys that hold up to a bulldog that chews. He loves these toys.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 31, 2026
A
Verified Purchase
Andy & Christie
Grantham, US
★★★★★ 5
My dogs love them
Size: Large, Style: Peanut Butter
One of the few toys my pit bulls can't break. They absolutely love these toys and play chase with them. Usually, they can break toys in less than 5 minutes, but not these.
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Reviewed in the United States on February 25, 2026
J
Verified Purchase
Jennifer Stellakis
Charlottesville, US
★★★★★ 5
Very durable and dont hurt teeth
Size: Large, Style: Peanut Butter
Dogs love - all 3 dogs have been playing with them for last week non stop. One bone is a little small for large dogs which is only reason its 4 stars
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Reviewed in the United States on February 20, 2026

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